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Kuai Yu Selected Research

Vitelliform Macular Dystrophy

12/2013Differential effects of Best disease causing missense mutations on bestrophin-1 trafficking.
3/2010Suppression of Ca2+ signaling in a mouse model of Best disease.
9/2009Dysregulation of human bestrophin-1 by ceramide-induced dephosphorylation.
4/2008Molecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathies.
11/2006The bestrophin mutation A243V, linked to adult-onset vitelliform macular dystrophy, impairs its chloride channel function.

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Kuai Yu Research Topics

Disease

9Neoplasms (Cancer)
12/2022 - 05/2009
6Macular Degeneration (Age-Related Maculopathy)
03/2010 - 10/2007
5Vitelliform Macular Dystrophy
12/2013 - 11/2006
2Cardiovascular Diseases (Cardiovascular Disease)
08/2022 - 01/2019
2Genetic Predisposition to Disease (Genetic Predisposition)
08/2022 - 03/2022
2Acute Coronary Syndrome
01/2021 - 01/2019
2Coronary Artery Disease (Coronary Atherosclerosis)
01/2020 - 12/2017
2Ischemia
01/2017 - 02/2015
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2022
1Leukemia
12/2022
1Immune System Diseases (Immune Disorders)
03/2022
1Spinal Cord Injuries (Spinal Cord Injury)
03/2022
1Stroke (Strokes)
11/2020
1Vascular Diseases (Vascular Disease)
11/2020
1Bites and Stings (Sting)
11/2020
1Rhabdomyosarcoma
01/2020
1Necrosis
06/2019
1Infections
06/2019
1Type 2L Limb-Girdle Muscular Dystrophy
11/2018
1Heart Failure
01/2017
1Brain Infarction
01/2017
1Ischemic Stroke
01/2017
1Brain Edema (Cerebral Edema)
01/2017
1Coronary Disease (Coronary Heart Disease)
01/2017
1Carcinogenesis
06/2014
1Hypertension (High Blood Pressure)
11/2013
1Hyperalgesia
11/2013
1Cystic Fibrosis (Mucoviscidosis)
11/2013
1Bronchitis
11/2013
1Asthma (Bronchial Asthma)
11/2013
1Retinal Detachment (Retinal Detachments)
03/2010
1Inflammation (Inflammations)
09/2009
1Hepatolenticular Degeneration (Wilson's Disease)
09/2005
1Seizures (Absence Seizure)
01/2003

Drug/Important Bio-Agent (IBA)

8BestrophinsIBA
12/2013 - 11/2006
5Chloride Channels (Chloride Channel)IBA
02/2015 - 11/2006
3Proteins (Proteins, Gene)FDA Link
11/2020 - 05/2009
3Biomarkers (Surrogate Marker)IBA
06/2019 - 06/2014
2ArsenicIBA
08/2022 - 03/2022
2AntigensIBA
01/2022 - 01/2020
2CopperIBA
01/2021 - 09/2005
2CytokinesIBA
01/2020 - 01/2019
1Biological ProductsIBA
12/2022
1InflammasomesIBA
12/2022
1Small Interfering RNA (siRNA)IBA
12/2022
1CurcuminIBA
12/2022
1Caspase 1 (ICE Protease)IBA
12/2022
1Transcription Factors (Transcription Factor)IBA
12/2022
1SeleniumIBA
08/2022
1HomocysteineIBA
08/2022
1MetalloidsIBA
08/2022
1MetalsIBA
08/2022
1Complement System Proteins (Complement)IBA
03/2022
1Messenger RNA (mRNA)IBA
01/2022
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2022
1Neoplasm Antigens (Tumor Antigens)IBA
01/2022
1Therapeutic UsesIBA
01/2022
1Small Cytoplasmic RNAIBA
01/2022
1VaccinesIBA
01/2022
1Diacylglycerol KinaseIBA
01/2021
1Carbon MonoxideIBA
11/2020
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2020
1Single-Chain AntibodiesIBA
01/2020
1Chimeric Antigen ReceptorsIBA
01/2020
1Interleukin-2 (IL2)IBA
01/2020
1InterferonsIBA
01/2020
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
01/2020
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2020
1Acute-Phase Proteins (Acute-Phase Protein)IBA
06/2019
1Fatty Acid-Binding ProteinsIBA
06/2019
1CarcinogensIBA
01/2019
1OsteopontinIBA
01/2019
1Hydrocortisone (Cortisol)FDA LinkGeneric
01/2019
1GlucocorticoidsIBA
01/2019
1Phospholipids (Phosphatides)FDA LinkGeneric
11/2018
1Carbon Nanotubes (Carbon Nanotube)IBA
01/2018
1LipidsIBA
12/2017
1NitrogenIBA
01/2017
1Urea (Carbamide)FDA LinkGeneric
01/2017
1LigandsIBA
01/2017
1EphA2 ReceptorIBA
01/2017
1Neuroprotective AgentsIBA
01/2017
1Anoctamin-1IBA
06/2014
1Photosensitizing Agents (Photosensitizers)IBA
02/2014
1Retinaldehyde (Retinal)IBA
12/2013
1Retinal Pigments (Pigments, Visual)IBA
03/2010
14-O-carboxymethylascochlorinIBA
03/2010
1LipofuscinIBA
03/2010
1CeramidesIBA
09/2009
1Ion Channels (Ion Channel)IBA
12/2008
1Membrane Proteins (Integral Membrane Proteins)IBA
04/2008
1PotassiumIBA
09/2005
1Glycine Receptors (Glycine Receptor)IBA
01/2003

Therapy/Procedure

4Therapeutics
03/2022 - 01/2020
2Immunotherapy
01/2022 - 01/2021
1Stem Cell Transplantation
03/2022
1Photochemotherapy (Photodynamic Therapy)
02/2014
1Drug Therapy (Chemotherapy)
11/2013